semaglutide (Ozmpic)5mg/3ml (1.66mg ml) Prefilled pen
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Ozmpic diet pen 10% discount on first 15 pens
5mg/3ml (1.66mg ml) Prefilled pen
For subcutaneous use only
Pen delivers doses of 0.25,0.5,0.75,1 or 1.25mg
Each box contains 4 x single use disposable needles
Semaglutide belongs to a class of drugs called glucagon-like peptide-1 (GLP-1) receptor agonists. It is used primarily for the treatment of type 2 diabetes, but it has also been approved by regulatory agencies in some countries for the treatment of obesity.
Mechanism of Action:
Semaglutide works by mimicking the action of a natural hormone called GLP-1. GLP-1 is released in response to food intake and helps regulate blood sugar levels by increasing insulin release, reducing glucagon secretion, and slowing down gastric emptying. Additionally, GLP-1 acts on the brain to induce a feeling of fullness or satiety. Semaglutide, as a GLP-1 receptor agonist, replicates these actions:
- Increased Insulin Release: Semaglutide helps the pancreas release more insulin, which lowers blood sugar levels.
- Reduced Glucagon Release: It decreases the release of glucagon, a hormone that raises blood sugar levels.
- Slowed Gastric Emptying: Semaglutide slows down the emptying of the stomach, leading to a sense of fullness and reduced food intake.
- Appetite Suppression: By acting on the brain’s satiety centers, Semaglutide can reduce appetite, leading to decreased calorie consumption.
Semaglutide has shown significant benefits for weight loss in clinical trials:
Substantial Weight Loss: In clinical trials, patients using Semaglutide have achieved significant weight loss, often exceeding 10% of their initial body weight.
Improved Metabolic Health: Along with weight loss, Semaglutide can lead to improvements in metabolic markers such as blood sugar control, blood pressure, and lipid profiles.
Appetite Control: Many individuals report reduced appetite while using Semaglutide, which can contribute to easier calorie restriction and weight loss.
Side Effects and How to Prevent Them:
While Semaglutide can be effective for weight loss, it is essential to be aware of potential side effects and how to manage them:
Gastrointestinal Symptoms: Common side effects include nausea, vomiting, diarrhea, and abdominal pain. These symptoms often occur when starting the medication but may improve over time. To prevent or minimize these side effects, it’s recommended to start with a lower dose and gradually increase it as tolerated.
Hypoglycemia: Semaglutide can lead to low blood sugar levels (hypoglycemia) when used in combination with other diabetes medications or insulin. To prevent hypoglycemia, follow your healthcare provider’s dosing instructions carefully and monitor your blood sugar regularly.
Pancreatitis: Rare cases of pancreatitis have been reported with Semaglutide. Be vigilant for symptoms like severe abdominal pain and seek medical attention if they occur.
The dosing of Semaglutide for weight loss may vary, but a common regimen is as follows:
The starting dose is usually 0.25 mg once a week for four weeks.
After the initial period, the dose is increased to 0.5 mg once a week.
Some individuals may eventually require an increased dose of 1.0 mg once a week for maximum efficacy.
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